Invention Grant
US08481581B2 S-triazolyl α-mercaptoacetanilides as inhibitors of HIV reverse transcriptase
有权
S-三唑基α-巯基乙酰替苯胺作为HIV逆转录酶的抑制剂
- Patent Title: S-triazolyl α-mercaptoacetanilides as inhibitors of HIV reverse transcriptase
- Patent Title (中): S-三唑基α-巯基乙酰替苯胺作为HIV逆转录酶的抑制剂
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Application No.: US13552443Application Date: 2012-07-18
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Publication No.: US08481581B2Publication Date: 2013-07-09
- Inventor: Jean-Luc Girardet , Yung-Hyo Koh , Martha De La Rosa , Esmir Gunic , Zhi Hong , Stanley Lang , Hong-Woo Kim
- Applicant: Jean-Luc Girardet , Yung-Hyo Koh , Martha De La Rosa , Esmir Gunic , Zhi Hong , Stanley Lang , Hong-Woo Kim
- Applicant Address: US CA San Diego
- Assignee: Ardea Biosciences, Inc.
- Current Assignee: Ardea Biosciences, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Wilson, Sonsini, Goodrich & Rosati
- Main IPC: A61K31/4196
- IPC: A61K31/4196 ; C07D249/08
Abstract:
A series of S-triazolyl α-mercaptoacetanilides having general structure (1) are provided, where Q is CO2H, CONR2, SO3H, or SO2NR2. The compounds inhibit several variants of the reverse transcriptase of HIV, and are useful in the treatment of HIV infections.
Public/Granted literature
- US20120283301A1 S-TRIAZOLYL ALPHA-MERCAPTO ACETANILIDES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE Public/Granted day:2012-11-08
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