Invention Grant
US08481600B2 Formulation of aspirin that is stable and showing minimal hydrolysis for parenteral administration for the treatment of cardiovascular and other disease states
有权
阿司匹林的制剂是稳定的，并且对于肠胃外给药用于治疗心血管疾病和其他疾病状态而显示出极小的水解
- Patent Title: Formulation of aspirin that is stable and showing minimal hydrolysis for parenteral administration for the treatment of cardiovascular and other disease states
- Patent Title (中): 阿司匹林的制剂是稳定的，并且对于肠胃外给药用于治疗心血管疾病和其他疾病状态而显示出极小的水解
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Application No.: US12454847Application Date: 2009-05-26
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Publication No.: US08481600B2Publication Date: 2013-07-09
- Inventor: John Charin Somberg , Vasant V Ranade
- Applicant: John Charin Somberg , Vasant V Ranade
- Applicant Address: US IL Lake Bluff
- Assignee: Academic Pharmaceuticals, Inc.
- Current Assignee: Academic Pharmaceuticals, Inc.
- Current Assignee Address: US IL Lake Bluff
- Agency: Vance Intellectual Property, PC
- Main IPC: A01N31/14
- IPC: A01N31/14 ; A61K31/075
Abstract:
Disclosed herein are ways to solubilize aspirin for parenteral administration containing aspirin and a diluent NNDMA (N,N-Dimethylacetamide) useful in the treatment of acute coronary syndromes as well as other disease states. The solution so constituted is stable at room temperature for prolonged periods without decomposition and avoids significant hydrolysis of the aspirin and thus the loss of the anti-platelet action when stored.
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