Invention Grant
US08481673B2 Bio-degradable/absorbable polymer having reduced metal catalyst content, and process for production thereof
失效
具有降低的金属催化剂含量的生物可降解/可吸收聚合物及其生产方法
- Patent Title: Bio-degradable/absorbable polymer having reduced metal catalyst content, and process for production thereof
- Patent Title (中): 具有降低的金属催化剂含量的生物可降解/可吸收聚合物及其生产方法
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Application No.: US13624207Application Date: 2012-09-21
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Publication No.: US08481673B2Publication Date: 2013-07-09
- Inventor: Hidetoshi Arimura , Yoshitake Takahashi , Koji Yamauchi
- Applicant: Gunze Limited
- Applicant Address: JP Ayabe-shi, Kyoto
- Assignee: Gunze Limited
- Current Assignee: Gunze Limited
- Current Assignee Address: JP Ayabe-shi, Kyoto
- Agency: Westerman, Hattori, Daniels & Adrian, LLP
- Priority: JP2006-178805 20060628; JP2006-178808 20060628
- Main IPC: C08G63/08
- IPC: C08G63/08

Abstract:
The present invention provides a method for reducing the content of a metal catalyst in a biodegradable and absorbable polymer that can be applied on an industrial scale and a method for producing a biodegradable and bioabsorbable polymer having a metal catalyst content of less than 1 ppm in terms of a metal. The method includes the steps of (1) copolymerizing lactide and ε-caprolactone at a molar ratio ranging from 40/60 to 60/40 or 65/35 to 85/15 in the presence of the metal catalyst to produce a copolymer; and (2) washing the copolymer with a mixed solvent comprising acetic acid and isopropanol at a volume ratio ranging from 25/75 to 45/55 or 45/55 to 55/45 at less than 40° C., and drying the copolymer.
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