Invention Grant
- Patent Title: Methods for detecting symmetrical dimethylarginine
- Patent Title (中): 检测对称二甲基精氨酸的方法
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Application No.: US12512479Application Date: 2009-07-30
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Publication No.: US08481690B2Publication Date: 2013-07-09
- Inventor: Yerramilli V. S. N. Murthy , Mahalakshmi Padmanabhan , Michael Atkinson , Kwok Kam Yeung
- Applicant: Yerramilli V. S. N. Murthy , Mahalakshmi Padmanabhan , Michael Atkinson , Kwok Kam Yeung
- Applicant Address: US ME Westbrook
- Assignee: IDEXX Laboratories, Inc.
- Current Assignee: IDEXX Laboratories, Inc.
- Current Assignee Address: US ME Westbrook
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/44

Abstract:
Method of detecting Symmetrical dimethyl arginine (SDMA) in biological samples. SDMA analogs for generating anti-SDMA antibodies having little or no cross-reactivity with asymmetrical dimethyl arginine, arginine, and monomethylarginine. The analogs have a protected or free thiol (—SH) group or hydroxyl (—OH) group that allow them to be linked to a suitable conjugation target which can be, for example, a protein containing molecule of a label. The anti-SDMA antibodies can be used in diagnostic immunoassay for the diagnosis of SDMA associated disorders and/or diseases.
Public/Granted literature
- US20100035274A1 Methods for Detecting Symmetrical Dimethylarginine Public/Granted day:2010-02-11
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