Invention Grant
- Patent Title: Method of synthesis of Bosentan, its polymorphic forms and its salts
- Patent Title (中): 波生坦合成方法及其多晶型及其盐
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Application No.: US12811279Application Date: 2009-01-02
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Publication No.: US08481730B2Publication Date: 2013-07-09
- Inventor: Dharmaraj Ramachandra Rao , Rajendra Narayanrao Kankan , Manjinder Singh Phull , Ashwini Amol Sawant
- Applicant: Dharmaraj Ramachandra Rao , Rajendra Narayanrao Kankan , Manjinder Singh Phull , Ashwini Amol Sawant
- Applicant Address: IN Mumbai
- Assignee: CIPLA Limited
- Current Assignee: CIPLA Limited
- Current Assignee Address: IN Mumbai
- Agency: Conley Rose, P.C.
- Agent Rodney B. Carroll
- Priority: IN12/MUM/2008 20080101; IN836/MUM/2008 20080409
- International Application: PCT/GB2009/000009 WO 20090102
- International Announcement: WO2009/083739 WO 20090709
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07D239/69 ; A61K31/506 ; A61P9/12
Abstract:
The present invention relates to alkaline earth metal salts of bosentan, anyhdrous bosentan, polymorphic forms thereof, amorphous bosentan and processes for preparing them. The present invention further relates to a process for the preparation of bosentan and its pharmaceutically acceptable salts.
Public/Granted literature
- US20110015394A1 Method of Synthesis of Bosentan, Its Polymorphic Forms and Its Salts Public/Granted day:2011-01-20
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