Invention Grant
- Patent Title: Fluorescent imaging with substituted cyanine dyes
- Patent Title (中): 用取代花青染料进行荧光成像
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Application No.: US12820077Application Date: 2010-06-21
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Publication No.: US08481752B2Publication Date: 2013-07-09
- Inventor: Xinshe Xu , Daniel R. Draney
- Applicant: Xinshe Xu , Daniel R. Draney
- Applicant Address: US NE Lincoln
- Assignee: Li-Cor, Inc.
- Current Assignee: Li-Cor, Inc.
- Current Assignee Address: US NE Lincoln
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: C12Q1/04
- IPC: C12Q1/04 ; C07K16/00 ; C07D209/56 ; C07D209/02
Abstract:
Compounds and methods are disclosed that are useful for noninvasive imaging in the near-infrared spectral range. The cyanine compounds of Formula I are presented: wherein Q is a portion of a polymethine bridge selected from the group consisting of: Also included are bioconjugates of the compounds of Formula I, methods of labeling biomolecules with the compounds, and methods of imaging.
Public/Granted literature
- US20100323389A1 FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES Public/Granted day:2010-12-23
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