Invention Grant
US08481778B2 Process for the preparation of esters of 4-fluorosubstituted 3-oxo-alcanoic acids
有权
制备4-氟取代的3-氧代 - 丙酸的酯的方法
- Patent Title: Process for the preparation of esters of 4-fluorosubstituted 3-oxo-alcanoic acids
- Patent Title (中): 制备4-氟取代的3-氧代 - 丙酸的酯的方法
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Application No.: US12673030Application Date: 2008-08-14
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Publication No.: US08481778B2Publication Date: 2013-07-09
- Inventor: Max Josef Braun
- Applicant: Max Josef Braun
- Applicant Address: BE Brussels
- Assignee: SOLVAY (Societe Anonyme)
- Current Assignee: SOLVAY (Societe Anonyme)
- Current Assignee Address: BE Brussels
- Agent Beatrice C. Ortego
- Priority: EP07114439 20070816
- International Application: PCT/EP2008/060674 WO 20080814
- International Announcement: WO2009/021987 WO 20090219
- Main IPC: C07C69/66
- IPC: C07C69/66
Abstract:
Esters of 4-fluorosubstituted 3-oxo-alcanoic acids can be prepared by addition reaction of ketene with the respective acid chloride, subsequent esterification and hydrodechlorination. Preferred reaction products are esters of 4,4-difluoro-3-oxo-butanoic acid.
Public/Granted literature
- US20110301378A1 Process for the preparation of esters of 4-fluorosubstituted 3-oxo-alcanoic acids Public/Granted day:2011-12-08
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