Invention Grant
- Patent Title: Treprostinil production
- Patent Title (中): 曲前列环素生产
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Application No.: US13151465Application Date: 2011-06-02
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Publication No.: US08481782B2Publication Date: 2013-07-09
- Inventor: Hitesh Batra , Raju Penmasta , Vijay Sharma , Sudersan M. Tuladhar , David A. Walsh
- Applicant: Hitesh Batra , Raju Penmasta , Vijay Sharma , Sudersan M. Tuladhar , David A. Walsh
- Applicant Address: US MD Silver Spring
- Assignee: United Therapeutics Corporation
- Current Assignee: United Therapeutics Corporation
- Current Assignee Address: US MD Silver Spring
- Agency: Foley & Lardner LLP
- Main IPC: C07C51/36
- IPC: C07C51/36
Abstract:
The present invention is directed to a novel method for preparing a synthetic intermediate for treprostinil via a stereoselective alkyne addition reaction. Also described are methods of preparing treprostinil comprising the alkyne addition reaction described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil.
Public/Granted literature
- US20110319641A1 TREPROSTINIL PRODUCTION Public/Granted day:2011-12-29
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