A sanitizer for sanitizing a portable electronic device is provided, the sanitizer having a base including a cavity for receiving the electronic device, at least one ultraviolet radiation source for emitting ultraviolet radiation into the cavity, a cover cooperating with the base, the cover moving between an open position wherein the electronic device can be inserted into or removed from the cavity and a closed position wherein the cavity is enclosed so as to substantially maintain the ultraviolet radiation within the cavity, and a controller for enabling the ultraviolet radiation source to be activated only when the cover is closed.