A system and method for detecting a rotation of the vehicle tires between different wheel locations. The method carried out by the system involves obtaining and storing TPM sensor identification numbers and their corresponding tire locations. Next, the system checks the sensors periodically to determine if any of the sensors have changed tire location. Based on that change, the system determines if a tire rotation has occurred; for example, by matching changes in sensor positions with known tire rotation patterns. This approach allows the system to detect and record a tire rotation, as well as to take some automated action, such as subsequently notifying the vehicle owner when the next scheduled tire rotation is due.