A method of controlling a driver-operated vehicle; the method including the steps of:recording the values of a number of psychophysical parameters of the driver over a first measuring interval; making a first evaluation of the driver's psychophysical condition on the basis of the driver's psychophysical parameter values over the first measuring interval; recording the values of the driver's psychophysical parameters over a second measuring interval following the first measuring interval; making a second evaluation of the driver's psychophysical condition on the basis of the driver's psychophysical parameter values over the second measuring interval; comparing the first and second evaluation of the driver's psychophysical condition to determine a change in the driver's psychophysical condition; and modifying the dynamic performance of the vehicle as a function of the driver's psychophysical condition, to adapt dynamic performance of the vehicle to the change in the driver's psychophysical condition.