An exemplary embodiment of portable electronic device with guide function includes a housing, a processing unit, a command unit, and a guiding unit. The processing unit and the guiding unit are positioned inside the housing, and the command unit is positioned at least partially outside of the housing. The processing unit is electrically connected to the command unit and the guiding unit. Operating the command unit, the portable electronic device with guide function is actuated into guiding mode controlled by the processing unit. The guiding unit sends detection signals to detect obstacles, receives feedback signals from the obstacles, the processing unit receives the feedback signal from the guiding unit to generate corresponding obstacle types and distance according to the feedback signal.