The present solution is directed towards systems and methods for managing cookies by a multi-core device. The device is intermediary to a client and one or more servers. A first core of a multi-core device receives a response from a server to a request of the client through a user session. The response comprises a cookie. The first core removes the cookie from the response and stores the cookie in a corresponding storage for the session. The first core forwards the response without the cookie to the client. A second core then receives via a session, a second request from the client. The second core determines the identification of the first core as owner of the session from the second request. The second core then communicates to the first core a third request for cookie information for the session.