Disclosed are systems and methods for computer malware detection. The system is configured to emulate execution of a program code, monitor events of program execution, classify the monitored events as malicious or non-malicious, and collect information about unclassifiable events. The system further includes one or more analyst workstations configured to isolate a program analyst from external audiovisual stimuli. The workstation includes a video output device operable to display a list of unclassifiable events and event-related information to the program analyst and a user input device operable to receive analyst's physiological response indicative of whether the displayed list of unclassifiable events exhibits malicious behavior.