Invention Grant
- Patent Title: Live virus vaccines
- Patent Title (中): 活病毒疫苗
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Application No.: US11816360Application Date: 2006-02-15
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Publication No.: US08486420B2Publication Date: 2013-07-16
- Inventor: Robert E. Johnston , Philip R. Johnson , Christy K. Jurgens , Kelly Young Poe
- Applicant: Robert E. Johnston , Philip R. Johnson , Christy K. Jurgens , Kelly Young Poe
- Applicant Address: US NC Chapel Hill US OH Columbus
- Assignee: The University of North Carolina at Chapel Hill,Children's Hospital, Inc.
- Current Assignee: The University of North Carolina at Chapel Hill,Children's Hospital, Inc.
- Current Assignee Address: US NC Chapel Hill US OH Columbus
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- International Application: PCT/US2006/005338 WO 20060215
- International Announcement: WO2007/046839 WO 20070426
- Main IPC: A61K39/21
- IPC: A61K39/21 ; C12N7/00

Abstract:
The present invention provides novel self-replicating and self-propagating chimeric viral vectors and chimeric virus particles comprising a modified genome of a carrier RNA virus packaged within structural proteins of a second virus. Also provided are pharmaceutical formulations comprising the chimeric viral vectors and virus particles and methods of inducing an immune response by administration of the same to a subject.
Public/Granted literature
- US20080260775A1 New Live Virus Vaccines Public/Granted day:2008-10-23
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