Invention Grant
US08486656B2 Method for prognosing response to cancer therapy with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine 有权
用5,10,15,20-四(羧基苯基)卟吩预防癌症治疗反应的方法

  • Patent Title: Method for prognosing response to cancer therapy with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine
  • Patent Title (中): 用5,10,15,20-四(羧基苯基)卟吩预防癌症治疗反应的方法
  • Application No.: US13158595
    Application Date: 2011-06-13
  • Publication No.: US08486656B2
    Publication Date: 2013-07-16
  • Inventor: Jeffrey L. Garwin
  • Applicant: Jeffrey L. Garwin
  • Applicant Address: US NM Albuquerque
  • Assignee: Biomoda, Inc.
  • Current Assignee: Biomoda, Inc.
  • Current Assignee Address: US NM Albuquerque
  • Agency: Peacock Myers, P.C.
  • Agent Janeen Vilven
  • Main IPC: G01N1/30
  • IPC: G01N1/30
Method for prognosing response to cancer therapy with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine
Abstract:
Presented is a method of prognosing a patient's response to a cancer therapy wherein prior to the therapy contacting a sample of cells from the patient's tissue or organ being treated for the cancer with a solution of TCPP to permit binding of the TCPP to components of the abnormal dysplastic or carcinomic cells, if any are present; detecting TCPP fluorescence in the sample, the presence of TCPP fluorescence being indicative that the sample contains dysplastic or carcinomic cells; at intervals during the therapy and subsequent to the therapy performing steps a-c on another sample of cells from the patient's tissue or organ being treated for the cancer; and determining if the percentage of abnormal pre-cancerous cells in the samples tested during and subsequent to the therapy are reduced as compared with the sample tested prior to the therapy, the reduction being prognostic of the patients response to the cancer therapy.
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