Invention Grant
US08486937B2 Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and use thereof
失效
吲唑，苯并噻唑，苯并异噻唑，苯并异恶唑及其制备和应用
- Patent Title: Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and use thereof
- Patent Title (中): 吲唑，苯并噻唑，苯并异噻唑，苯并异恶唑及其制备和应用
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Application No.: US13165370Application Date: 2011-06-21
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Publication No.: US08486937B2Publication Date: 2013-07-16
- Inventor: Wenge Xie , Brian Herbert , Richard A. Schumacher , Truc Minh Nguyen , Jianguo Ma , Carla Maria Gauss , Ashok Tehim
- Applicant: Wenge Xie , Brian Herbert , Richard A. Schumacher , Truc Minh Nguyen , Jianguo Ma , Carla Maria Gauss , Ashok Tehim
- Applicant Address: US NJ Montvale
- Assignee: Memory Pharmaceuticals Corporation
- Current Assignee: Memory Pharmaceuticals Corporation
- Current Assignee Address: US NJ Montvale
- Agency: Millen, White, Zelano & Branigan, P.C.
- Main IPC: A61K31/439
- IPC: A61K31/439 ; A61K31/4545 ; A61K31/5377 ; A61P3/10 ; A61P25/16 ; A61P25/18 ; A61P25/24 ; C07D453/02
Abstract:
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles), which act as ligands for the α7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
Public/Granted literature
- US20110319407A1 INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USE THEREOF Public/Granted day:2011-12-29
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