Invention Grant
US08487001B2 Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors
有权
中链长度脂肪酸，甘油酯和类似物作为嗜中性粒细胞存活和激活因子
- Patent Title: Medium-chain length fatty acids, glycerides and analogues as neutrophil survival and activation factors
- Patent Title (中): 中链长度脂肪酸，甘油酯和类似物作为嗜中性粒细胞存活和激活因子
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Application No.: US12814028Application Date: 2010-06-11
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Publication No.: US08487001B2Publication Date: 2013-07-16
- Inventor: Lyne Gagnon , Jean Barabe , Pierre Laurin , Christopher Penney , Boulos Zacharie
- Applicant: Lyne Gagnon , Jean Barabe , Pierre Laurin , Christopher Penney , Boulos Zacharie
- Applicant Address: CA Laval, Quebec
- Assignee: ProMetic BioSciences Inc.
- Current Assignee: ProMetic BioSciences Inc.
- Current Assignee Address: CA Laval, Quebec
- Agent France LeClaire
- Main IPC: A61K31/7024
- IPC: A61K31/7024 ; A61K31/23 ; A61K31/22 ; A61K31/198 ; C07C235/06 ; C07C235/12 ; A61P7/00
Abstract:
A composition and method for promoting neutrophil survival and activation such as the treatment of neutropenia arising as an undesirable side effect of chemotherapy and radiation therapy. A composition containing medium-chain fatty acids, such as Capri acid or caprylic acid, or salts or triglycerides thereof, or mono- or diglycerides or other analogues thereof or medium-chain triglycerides (MCT) is administered to a human or animal needing treatment in an amount sufficient to reduce or eliminate neutropenia. The composition is administered in an amount effective to treat the disorder. The methods are also useful in the management of bone narrow transplantation and in the treatment of various neutropenic diseases.
Public/Granted literature
- US20100279959A1 Medium-Chain Length Fatty Acids, Glycerides and Analogues as Neutrophil Survival and Activation Factors Public/Granted day:2010-11-04
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