In various embodiments, applicants' teachings are related to an active guarding circuit and method for reducing parasitic impedance signal loading on a signal-transmission channel that is shunted by a parasitic impedance. The presence of an electrical signal on the signal-transmission channel causes a leakage current to flow through the parasitic impedance. In various embodiments, the circuit comprises an amplifier and an impedance, one terminal of the impedance is coupled to the signal-transmission channel. The input of the amplifier is coupled to the signal-transmission channel and the output is coupled to the other terminal of the impedance so as to cause a compensation current to flow through the impedance. The gain of the amplifier and the value of the impedance are selected so that the compensation current has a magnitude substantially equal to the leakage current magnitude.