A method and apparatus for transmitting/receiving a Random Access Channel (RACH) signal in a communication system. A User Equipment (UE) selects one of Contention Resolution (CR) channels allocated for collision detection, and transmits the selected CR channel and a connection request message to an Evolved Node B (E-NB), and receives a response signal from the E-NB. The UE transmits the RACH signal, if a collision indicator is included in the response signal. The E-NB receives from each of UEs a connection request message and a CR channel, decodes the connection request message, and detects a collision between the UEs using the CR channel. The E-NB generates a response signal to the connection request message according to the decoding result, generates a collision indicator according to the collision detection result, and transmits to the UEs at least one of the generated response signal, the generated collision indicator, and a unique ID of a corresponding UE.