Invention Grant
- Patent Title: Crystalline composition of GM-CSF/GM-CSFR
- Patent Title (中): GM-CSF / GM-CSFR的结晶组成
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Application No.: US12513497Application Date: 2007-11-01
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Publication No.: US08489339B2Publication Date: 2013-07-16
- Inventor: Guido Hansen , Timothy Robert Hercus , Angel Francisco Lopez , William John McKinstry , Michael William Parker
- Applicant: Guido Hansen , Timothy Robert Hercus , Angel Francisco Lopez , William John McKinstry , Michael William Parker
- Applicant Address: AU AU
- Assignee: St. Vincent's Institute of Medical Research,Central Adelaide Local Health Network
- Current Assignee: St. Vincent's Institute of Medical Research,Central Adelaide Local Health Network
- Current Assignee Address: AU AU
- Agency: Knobbe Martens Olson & Bear, LLP
- International Application: PCT/AU2007/001674 WO 20071101
- International Announcement: WO2008/052277 WO 20080508
- Main IPC: G01N23/02
- IPC: G01N23/02
Abstract:
The present invention relates generally to the field of crystallography. More particularly, the present invention provides crystalline forms of a complex between granulocyte macrophage-colony stimulating factor (GM-CSF) and its receptor (GM-CSFR). The present invention further provides methods for the design and selection of modulators of GM-CSF/GM-CSFR interaction and signaling as well as signaling of other cytokines.
Public/Granted literature
- US20110150884A1 CRYSTALLINE COMPOSITION OF GM-CSF/GM-CSFR Public/Granted day:2011-06-23
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