The present invention relates to a wireless protocol adapter assembly for diagnostics, analysis, and monitoring. The wireless protocol adapter assembly provides a common connection interface between a sealed common electronics package and a plurality of vehicle connectors that access a plurality of vehicle networks respectively for translating and transferring signals between the plurality of in-vehicle networks and a host computer. The common connection interface allows the vehicle connector compatible with a particular vehicle type to be coupled to the common electronics package. The common electronics package can recognizes when it is connected to a vehicle network running a particular protocol and automatically switch to that protocol. A wireless protocol adapter board having a standard connection pinning arrangement allows wireless links to be changed or altered as wireless standards change and evolve.