Invention Grant
US08491910B2 Vaccine comprising AMB A 1 peptides for use in the treatment of ragweed allergy
有权
包含用于治疗豚草过敏的AMB A 1肽的疫苗
- Patent Title: Vaccine comprising AMB A 1 peptides for use in the treatment of ragweed allergy
- Patent Title (中): 包含用于治疗豚草过敏的AMB A 1肽的疫苗
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Application No.: US13057386Application Date: 2009-08-14
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Publication No.: US08491910B2Publication Date: 2013-07-23
- Inventor: Mark Larche , Roderick Peter Hafner , Paul Laidler
- Applicant: Mark Larche , Roderick Peter Hafner , Paul Laidler
- Applicant Address: GB Oxford
- Assignee: Circassia Limited
- Current Assignee: Circassia Limited
- Current Assignee Address: GB Oxford
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Jeanne M. DiGiorgio
- Priority: GB0814986.6 20080815; WOPCT/GB08/002779 20080815; WOPCT/GB08/002781 20080815; GB0815218.3 20080820; EP09251252 20090501
- International Application: PCT/GB2009/001986 WO 20090814
- International Announcement: WO2010/018378 WO 20100218
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/04 ; A61K39/00 ; A61K39/35 ; A61K39/36 ; A61K39/38 ; C07K2/00 ; C07K4/00 ; C07K5/00 ; C07K7/00 ; C07K14/00 ; C07K16/00
Abstract:
The present invention relates to compositions for preventing or treating allergy to ragweed by tolerization. The compositions are based on combinations of peptide fragments derived from the major allergen in ragweed pollen, Amb a 1. The invention also relates to products, vectors and formulations which may be used to provide polypeptides of the invention in combination. The invention further relates to in vitro methods for determining whether T cells recognize a polypeptide of the invention, and for determining whether an individual has or is at risk of a condition characterized by allergic symptoms in response to a ragweed allergen.
Public/Granted literature
- US20120108524A1 VACCINE COMPRISING AMB A 1 PEPTIDES FOR USE IN THE TREATMENT OF RAGWEED ALLERGY Public/Granted day:2012-05-03
Information query
IPC分类:
