Invention Grant
US08492160B1 Biomarker sensors and method for multi-color imaging and processing of single-molecule life signatures
有权
生物标记传感器和多色成像和处理单分子生命特征的方法
- Patent Title: Biomarker sensors and method for multi-color imaging and processing of single-molecule life signatures
- Patent Title (中): 生物标记传感器和多色成像和处理单分子生命特征的方法
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Application No.: US12720103Application Date: 2010-03-09
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Publication No.: US08492160B1Publication Date: 2013-07-23
- Inventor: Lawrence A. Wade , Charles Patrick Collier
- Applicant: Lawrence A. Wade , Charles Patrick Collier
- Applicant Address: US DC Washington
- Assignee: The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration
- Current Assignee: The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration
- Current Assignee Address: US DC Washington
- Agent Mark Homer
- Main IPC: G01N1/28
- IPC: G01N1/28 ; C12N13/00
Abstract:
The invention is a device including array of aciive regions for use in reacting one or more species in at least two of the active regions in a sequential process, e.g., sequential reactions. The device has a transparent substrate member, which has a surface region and a silane material overlying the surface region. A first active region overlies a first portion of the silane material. The first region has a first dimension of less than 1 micron in size and has first molecules capable of binding to the first portion of the silane material. A second active region overlies a second portion of the silane material. The second region has a second dimension of less than 1 micron in size, second molecules capable of binding to the second portion of the active region, and a spatial distance separates the first active region and the second active region.
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