Invention Grant
- Patent Title: Method for modifying nucleic acid bases, and nucleic acid base-modified product
- Patent Title (中): 核酸碱基修饰方法和核酸碱基修饰产物
-
Application No.: US12672649Application Date: 2008-08-08
-
Publication No.: US08492536B2Publication Date: 2013-07-23
- Inventor: Masanori Kataoka , Kuniaki Nagayama
- Applicant: Masanori Kataoka , Kuniaki Nagayama
- Applicant Address: JP Tokyo US NY New York
- Assignee: Inter-University Research Institute Corporation National Institute of Natural Sciences,Nagayama IP Holdings, LLC
- Current Assignee: Inter-University Research Institute Corporation National Institute of Natural Sciences,Nagayama IP Holdings, LLC
- Current Assignee Address: JP Tokyo US NY New York
- Agency: Jordan and Hamburg LLP
- Priority: JP2007-207083 20070808; JP2007-233592 20070910
- International Application: PCT/JP2008/064619 WO 20080808
- International Announcement: WO2009/020249 WO 20090212
- Main IPC: C07H21/00
- IPC: C07H21/00
Abstract:
A method for modifying nucleic acid bases by a chemical means, which enables the discrimination of every base species in plural species of bases in a nucleic acid comprising plural nucleotide units, while retaining the base sequence information of the nucleic acid. A nucleic acid base-modified product provided by the method. The nucleic acid base-modified product is essentially a single strand. In accordance with the invention, a novel means for sequencing a nucleic acid by a microscopic means is provided.
Public/Granted literature
Information query
