Various techniques are provided for processing image data acquired using a digital image sensor. In accordance with aspects of the present disclosure, one such technique may relate to the processing of image data in a system that supports multiple image sensors. In one embodiment, the image processing system may include control circuitry configured to determine whether a device is operating in a single sensor mode (one active sensor) or a dual sensor mode (two active sensors). When operating in the single sensor mode, data may be provided directly to a front-end pixel processing unit from the sensor interface of the active sensor. When operating in a dual sensor mode, the image frames from the first and second sensors are provided to the front-end pixel processing unit in an interleaved manner. For instance, in one embodiment, the image frames from the first and second sensors are written to a memory, and then read out to the front-end pixel processing unit in an interleaved manner.