Invention Grant
- Patent Title: Data transformation methods for multiplexed assays
- Patent Title (中): 用于多重测定的数据转换方法
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Application No.: US12698785Application Date: 2010-02-02
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Publication No.: US08494780B2Publication Date: 2013-07-23
- Inventor: Lance F. Bentley Tammero , John M. Dzenitis , Benjamin J. Hindson
- Applicant: Lance F. Bentley Tammero , John M. Dzenitis , Benjamin J. Hindson
- Applicant Address: US CA Livermore
- Assignee: Lawrence Livermore National Security, LLC
- Current Assignee: Lawrence Livermore National Security, LLC
- Current Assignee Address: US CA Livermore
- Agency: Steinfl & Bruno, LLP
- Main IPC: G06F19/24
- IPC: G06F19/24 ; G06F19/20 ; C12Q1/68 ; G01N33/53 ; G01N33/569
Abstract:
Methods to improve the performance of an array assay are described. A correlation between fluorescence intensity-related parameters and negative control values of the assay is determined. The parameters are then adjusted as a function of the correlation. As a result, sensitivity of the assay is improved without changes in its specificity.
Public/Granted literature
- US20110022344A1 DATA TRANSFORMATION METHODS FOR MULTIPLEXED ASSAYS Public/Granted day:2011-01-27
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