Methods and structure within a storage system for tuning performance of the storage system based on monitored block level access within the storage system. Block level access, either in cache memory or on the storage devices of the storage system, is monitored to detect patterns of access and/or data that correspond to an identified host system program. Based on the identified host system program, a profile of desired storage device configuration information is selected by the storage system. The profile comprises information identifying optimal configuration of a logical volume used by the corresponding host system program. Reconfiguration options are identified from the profile information and used either to automatically reconfigure the logical volume or are presented to a user to permit the user to select desired options from the reconfiguration options.