A bone screw retention system is provided for a plate which defines a plurality of transversely extending bores that are configured to receive a bone screw for engaging the plate to the cervical spine. One or more retention members, having an elliptical, arcuate, straight, or other shape, can be positioned therein a cavity of the plate such that portions of the retention member(s) extend into a portion of an upper region of each bore to retain a bone screw therein. A bone screw removal device is provided, having at least one tongue member configured to selectively displace the one or more retention members to allow the bone screw to be removed from the respective bore.