Invention Grant
- Patent Title: VHNAR anti-cytokine domains
- Patent Title (中): VHNAR抗细胞因子结构域
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Application No.: US12939195Application Date: 2010-11-04
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Publication No.: US08496933B2Publication Date: 2013-07-30
- Inventor: Jorge F. Paniagua-Solís , María Teresa Mata-González , Walter J. García-Ubbelohde , Araceli Olguín-Jimenez , Alexei F. Licea-Navarro , Tanya A. Camacho-Villegas , Edna Sanchez-Castrejon
- Applicant: Jorge F. Paniagua-Solís , María Teresa Mata-González , Walter J. García-Ubbelohde , Araceli Olguín-Jimenez , Alexei F. Licea-Navarro , Tanya A. Camacho-Villegas , Edna Sanchez-Castrejon
- Applicant Address: MX Delegacion Benito Juarez
- Assignee: Laboratorios Silanes, S.A. de C.V.
- Current Assignee: Laboratorios Silanes, S.A. de C.V.
- Current Assignee Address: MX Delegacion Benito Juarez
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K38/16 ; C07K16/22
Abstract:
The present invention concerns therapeutic compositions containing proteins that are the variable regions of IgNAR immunoglobulins, denominated vNAR, that specifically bind and neutralizes cytokines involved in a diversity of process such as inflammation and neovascularization, its ability to reach, bind, and neutralize the activity of one antigenic molecule localized in an immunoprivileged organs, are also described.
Public/Granted literature
- US20110129473A1 VHNAR ANTI-CYTOKINE DOMAINS Public/Granted day:2011-06-02
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