Invention Grant
- Patent Title: Processes for intermediates for macrocyclic compounds
- Patent Title (中): 大环化合物中间体的方法
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Application No.: US13036484Application Date: 2011-02-28
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Publication No.: US08497242B2Publication Date: 2013-07-30
- Inventor: Éric Marsault , Kamel Benakli , Hamid R. Hoveyda , Mark L. Peterson , Sylvie Beaubien , Luc Ouellet , Carl St-Louis , Sophie Beauchemin
- Applicant: Éric Marsault , Kamel Benakli , Hamid R. Hoveyda , Mark L. Peterson , Sylvie Beaubien , Luc Ouellet , Carl St-Louis , Sophie Beauchemin
- Applicant Address: CA
- Assignee: Tranzyme Pharma Inc.
- Current Assignee: Tranzyme Pharma Inc.
- Current Assignee Address: CA
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- Main IPC: A61K38/25
- IPC: A61K38/25

Abstract:
The present invention is directed to novel macrocyclic compounds of formula (I) and their pharmaceutically acceptable salts, hydrates or solvates: wherein R1, R2, R3, R4, R5, R6, n1, m, p Z1, Z2, and Z3 are as describe in the specification. The invention also relates to compounds of formula (I) which are antagonists of the motilin receptor and are useful in the treatment of disorders associated with this receptor and with or with motility dysfunction.
Public/Granted literature
- US20110245459A1 Processes for Intermediates for Macrocyclic Compounds Public/Granted day:2011-10-06
Information query
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