Invention Grant
- Patent Title: Pyrrolinone derivative and pharmaceutical composition comprising the same
- Patent Title (中): 吡咯啉酮衍生物及其组合物
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Application No.: US13242518Application Date: 2011-09-23
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Publication No.: US08497263B2Publication Date: 2013-07-30
- Inventor: Hiroyuki Kai , Shunji Shinohara , Takayuki Kameyama
- Applicant: Hiroyuki Kai , Shunji Shinohara , Takayuki Kameyama
- Applicant Address: JP Osaka
- Assignee: Shionogi & Co., Ltd.
- Current Assignee: Shionogi & Co., Ltd.
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2007-091624 20070330
- Main IPC: A61K31/422
- IPC: A61K31/422 ; A61K31/454 ; A61K31/551 ; A61K31/4439 ; A61K31/4025 ; C07D413/14 ; C07D487/04 ; C07D413/10 ; C07D207/26 ; C07D261/06

Abstract:
The present invention provides a compound represented by the formula (I): wherein R1, R2, R3, Z1, Z2, Ra, Rb, q, A and n are as defined in the description, a pharmaceutically acceptable salt or solvate thereof. The compound is useful as P2X3 and/or P2X2/3 receptor antagonist.
Public/Granted literature
- US20120010199A1 NOVEL PYRROLINONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME Public/Granted day:2012-01-12
Information query
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