Invention Grant
US08497266B2 3-(3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyridazine derivatives as MET kinase inhibitors
有权
3-（3-嘧啶-2-基苄基）-1,2,4-三唑并[4,3-b]哒嗪衍生物作为MET激酶抑制剂
![3-(3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyridazine derivatives as MET kinase inhibitors](/docs/US/2013-07-30/US08497266B2/abs.jpg.600x600.jpg)
- Patent Title: 3-(3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyridazine derivatives as MET kinase inhibitors
- Patent Title (中): 3-（3-嘧啶-2-基苄基）-1,2,4-三唑并[4,3-b]哒嗪衍生物作为MET激酶抑制剂
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Application No.: US12999873Application Date: 2009-05-25
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Publication No.: US08497266B2Publication Date: 2013-07-30
- Inventor: Dieter Dorsch , Oliver Schadt , Frank Stieber , Andree Blaukat
- Applicant: Dieter Dorsch , Oliver Schadt , Frank Stieber , Andree Blaukat
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: DE102008028905 20080618
- International Application: PCT/EP2009/003675 WO 20090525
- International Announcement: WO2009/152920 WO 20091223
- Main IPC: A61K31/50
- IPC: A61K31/50 ; A61K31/495 ; C07D471/04
![3-(3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyridazine derivatives as MET kinase inhibitors](/abs-image/US/2013/07/30/US08497266B2/abs.jpg.150x150.jpg)
Abstract:
Compounds of the formula (I), in which R1, R2, R3, R3′, R4 have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular of Met kinase, and can be employed, inter alia, for the treatment of tumors.
Public/Granted literature
- US20110092498A1 3-(3-PYRIMIDIN-2-YLBENZYL)-1,2,4-TRIAZOLO[4,3-B]PYRIDAZINE DERIVATIVES AS MET KINASE INHIBITORS Public/Granted day:2011-04-21
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