Invention Grant
US08497287B2 Aminotetralin compounds as mu opioid receptor antagonists 有权
氨基四氢萘化合物作为μ阿片受体拮抗剂

Aminotetralin compounds as mu opioid receptor antagonists
Abstract:
The invention provides aminotetralin compounds of formula (I): wherein R1, R2, R3, R4, R5, R6, R7, n, and m are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and intermediates useful for preparing such compounds.
Public/Granted literature
Information query
Patent Agency Ranking
0/0