Invention Grant
- Patent Title: Carboxylic acid derivative containing thiazole ring and pharmaceutical use thereof
- Patent Title (中): 含有噻唑环的羧酸衍生物及其药物用途
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Application No.: US13132292Application Date: 2009-12-01
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Publication No.: US08497382B2Publication Date: 2013-07-30
- Inventor: Naoko Ando
- Applicant: Naoko Ando
- Applicant Address: JP Osaka-Shi
- Assignee: Mitsubishi Tanabe Pharma Corporation
- Current Assignee: Mitsubishi Tanabe Pharma Corporation
- Current Assignee Address: JP Osaka-Shi
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2008-306803 20081201
- International Application: PCT/JP2009/070185 WO 20091201
- International Announcement: WO2010/064633 WO 20100610
- Main IPC: A61K31/426
- IPC: A61K31/426 ; C07D277/36

Abstract:
A compound represented by the formula (I) wherein R1 and R2 are each a hydrogen atom, an alkyl group and the like, R3 is a hydrogen atom, an alkyl group and the like, R4 is a hydrogen atom, an alkyl group and the like, m is an integer of 0 to 3, X is a bond, an oxygen atom or a sulfur atom, Y is a carbonyl group, a hydroxymethylene group and the like, and Z is a halogen atom, an alkyl group, an aryl group, a heteroaryl group and the like, or a pharmaceutically acceptable salt thereof has a superior PPARα agonist action and a lipid-lowering action, and is useful as a prophylactic or therapeutic drug for hyperlipidemia and the like.
Public/Granted literature
- US20110237630A1 CARBOXYLIC ACID DERIVATIVE CONTAINING THIAZOLE RING AND PHARMACEUTICAL USE THEREOF Public/Granted day:2011-09-29
Information query
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