Invention Grant
- Patent Title: Phospholipid-analogous compounds
- Patent Title (中): 磷脂类似物
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Application No.: US13084876Application Date: 2011-04-12
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Publication No.: US08497388B2Publication Date: 2013-07-30
- Inventor: Hans-Jörg Eibl
- Applicant: Hans-Jörg Eibl
- Applicant Address: DE Munich
- Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften. e.V.
- Current Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften. e.V.
- Current Assignee Address: DE Munich
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- Priority: DE19735776 19970818
- Main IPC: C07F9/02
- IPC: C07F9/02

Abstract:
Phospholipid-analogous compounds of the general formula (I) in which a is b is where R1 and R2 are, independently of one another, hydrogen, a saturated or unsaturated acyl or alkyl radical which can optionally be branched or/and substituted, where the total of the carbon atoms in the acyl and alkyl is 16 to 44 C atoms, s is an integer from 0 to 8, c is a radical of a primary or secondary alcohol of the formula RO—, where R is a saturated or unsaturated alkyl radical, mainly with cis double bond, of froth 12 to 30 carbon atoms, n is an integer from 2 to 8, R3 a can be 1,2-dihydroxypropyl or b can be alkyl with 1 to 3 C atoms when z is >0 or c can be alkyl with 1 to 3 carbon atoms when n≠2 and z=0, m is 1 or 2, x is an integer from 0 to 8, y is 1 for z=1 to 5 or is 1 to 4 for z=1 z is an integer from 0 to 5, are novel and are suitable as liposome constituents, solubilizers and pharmaceuticals.
Public/Granted literature
- US20120009246A1 PHOSPHOLIPID-ANALOGOUS COMPOUNDS Public/Granted day:2012-01-12
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