Method for inspecting a zone of the surface of a tire, said surface comprising markings in relief, wherein the three-dimensional profile of the surface to be inspected is determined, characteristic points on the surface to be inspected are located and these points are matched with the corresponding points originating from the three-dimensional data of a reference surface, so as to create a set of pairs of matched points, in an iterative manner, a first affine transformation function is sought, applied to the characteristic points of the reference surface, so that the value representing the sum of the distances between each of the characteristic points of the reference surface, which points are transformed with the aid of said first transformation function, and the points of the surface to be inspected that are matched with them, is minimal, and said first transformation function is applied to all of the points of the reference surface in order to obtain a transformed reference surface.