A post-operative pain inhibitor system comprises a controller and leads. Neuro-stimulator circuitry may be included within the patient controller or within one or more prosthetic components for generating a signal. In one example, an electrode is configured to be attached to skin in proximity to an operative field of an implanted joint. Topical leads, percutaneous leads, subcutaneous leads, intraosseous leads, or leads can also be placed in proximity to the operative field corresponding to the prosthetic component installation. The lead or electrodes can be coupled to neuro-stimulation circuitry to stimulate peripheral nerve fibers to affect body generated action potentials. A transmitter or power source can be housed in a prosthetic component. The controller can modify the pulse width, pulse shape, pulse repetition rate, and pulse amplitude of the signal thereby allowing the patient to adapt the signal to minimize their perceived pain.