A muzzle loading firearm has a barrel with a bore on a bore axis, and has a muzzle end and a breech end. A frame is connected to the barrel, and has a breech face. The frame moves between an open position in which the breech face is away from the breech end of the barrel, and a closed position in which the breech face abuts the breech end of the barrel. A breech plug is removably attached to the barrel, and is connected to the barrel by way of interrupted, or multistart threads, or locking lugs. The breech plug may have a rear face that abuts the breech face when the frame is closed, so that a primer contained in a primer pocket in the rear of the breech plug is fully supported on all sides.