Invention Grant
- Patent Title: Injectable multimodal polymer depot compositions and uses thereof
- Patent Title (中): 可注射多峰聚合物储库组合物及其用途
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Application No.: US10628984Application Date: 2003-07-28
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Publication No.: US08501215B2Publication Date: 2013-08-06
- Inventor: Guohua Chen , Paul Houston , Lothar Kleiner , Jeremy Wright
- Applicant: Guohua Chen , Paul Houston , Lothar Kleiner , Jeremy Wright
- Main IPC: A61F2/00
- IPC: A61F2/00 ; A61F13/00 ; A61K9/14

Abstract:
Injectable depot compositions are provided that include a polymer matrix having a plurality of bioerodible, biocompatible polymers wherein each polymer of the plurality of polymers has a specified average molecular weight, and the polymer matrix has a broad molecular weight distribution of the plurality of polymers; a solvent having a miscibility in water of less than or equal to 7 wt % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith; and a beneficial agent. The compositions have substantially improved shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.
Public/Granted literature
- US20040022859A1 Injectable multimodal polymer depot compositions and uses thereof Public/Granted day:2004-02-05
Information query
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