The present invention discloses a reactive monomer of liquid crystal. The reactive monomer of liquid crystal is added with at least one fluoro group. Because hydrocarbon bonds of a side chain of polyimide surface of an alignment film has a fluorophobic effect, the fluoro group of the reactive monomer of liquid crystal can lower the interaction between the polyimide surface of the alignment film and the reactive monomer of liquid crystal to thus evenly deposit the liquid crystal composition containing the reactive monomers of liquid crystal onto the polyimide surface of the alignment film. Thus, it can avoid from occurring the phenomenon of drop Mura defect occurred during implementing the ODF technology.