Invention Grant
- Patent Title: Gnaq mutations in melanoma
- Patent Title (中): Gnaq突变黑色素瘤
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Application No.: US12526449Application Date: 2008-02-08
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Publication No.: US08501404B2Publication Date: 2013-08-06
- Inventor: Boris C. Bastian , Catherine D. Van Raamsdonk , Gregory S. Barsh
- Applicant: Boris C. Bastian , Catherine D. Van Raamsdonk , Gregory S. Barsh
- Applicant Address: US CA Oakland US CA Palo Alto CA Vancouver, BC
- Assignee: The Regents of the University of California,The Board of Trustees of the Leland Stanford Junior University,The University of British Columbia
- Current Assignee: The Regents of the University of California,The Board of Trustees of the Leland Stanford Junior University,The University of British Columbia
- Current Assignee Address: US CA Oakland US CA Palo Alto CA Vancouver, BC
- Agency: Kilpatrick Townsend & Stockton LLP
- International Application: PCT/US2008/053484 WO 20080208
- International Announcement: WO2008/098208 WO 20080814
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The present invention provides methods of detecting mutations in a Gnaq gene in a melanocytic neoplasm for diagnostic and prognostic purposes. The invention further provides methods of treating such melanocytic neoplasm by modulating the activity of the mutated Gnaq gene.
Public/Granted literature
- US20110070221A1 GNAQ MUTATIONS IN MELANOMA Public/Granted day:2011-03-24
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