Invention Grant
- Patent Title: Overexpression of Wnt ligands and treatment of lytic bone diseases
- Patent Title (中): Wnt配体的过表达和溶骨症的治疗
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Application No.: US11999301Application Date: 2007-12-04
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Publication No.: US08501702B2Publication Date: 2013-08-06
- Inventor: John D. Shaughnessy, Jr. , Ya-wei Qiang , Shmuel Yaccoby
- Applicant: John D. Shaughnessy, Jr. , Ya-wei Qiang , Shmuel Yaccoby
- Applicant Address: US AR Little Rock
- Assignee: Broad of Trustees of the University of Arkansas
- Current Assignee: Broad of Trustees of the University of Arkansas
- Current Assignee Address: US AR Little Rock
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- Main IPC: A61K48/00
- IPC: A61K48/00 ; A61K39/395
Abstract:
The present invention is drawn to methods of repairing lytic bone lesions and tumor growth in an individual. In this regard, the present invention discloses use of a Wnt ligand either alone or in combination with anti-Wnt signaling antagonist therapy. The individuals who might benefit from such method may include but are not limited to the ones with multiple myeloma, osteoporosis, post-menopausal osteoporosis, fractures, metastatic breast cancer or metastatic prostate cancer.
Public/Granted literature
- US20080193515A1 Overexpression of Wnt ligands and treatment of lytic bone diseases Public/Granted day:2008-08-14
Information query
