Invention Grant
US08501731B2 Derivatives of 6[3-(trifluoromethyl)phenyl]pyridazin-3(2H)-one having antitumor activity
有权
具有抗肿瘤活性的6 [3-（三氟甲基）苯基]哒嗪-3（2H） - 酮的衍生物
![Derivatives of 6[3-(trifluoromethyl)phenyl]pyridazin-3(2H)-one having antitumor activity](/docs/US/2013-08-06/US08501731B2/abs.jpg.600x600.jpg)
- Patent Title: Derivatives of 6[3-(trifluoromethyl)phenyl]pyridazin-3(2H)-one having antitumor activity
- Patent Title (中): 具有抗肿瘤活性的6 [3-（三氟甲基）苯基]哒嗪-3（2H） - 酮的衍生物
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Application No.: US12933104Application Date: 2009-03-18
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Publication No.: US08501731B2Publication Date: 2013-08-06
- Inventor: Youhong Hu , Liguang Lou , Shijun Lin , Hongbing Zhao , Zhende Liu , Yongping Xu , Bo Chao
- Applicant: Youhong Hu , Liguang Lou , Shijun Lin , Hongbing Zhao , Zhende Liu , Yongping Xu , Bo Chao
- Applicant Address: CN Shanghai
- Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- Current Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
- Current Assignee Address: CN Shanghai
- Agency: Kramer & Amado, P.C.
- Priority: CN200810034796 20080318
- International Application: PCT/CN2009/000295 WO 20090318
- International Announcement: WO2009/114993 WO 20090924
- Main IPC: C07D403/10
- IPC: C07D403/10 ; C07D401/10 ; C07D277/04 ; C07D237/04 ; C07D413/10 ; A61K31/55 ; A61K31/501 ; A61P35/00
![Derivatives of 6[3-(trifluoromethyl)phenyl]pyridazin-3(2H)-one having antitumor activity](/abs-image/US/2013/08/06/US08501731B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to a class of pyridazinones of formula I, which comprises 6-[3-(trifluoromethyl)phenyl]pyridazin-3(2H)-one as a mother nucleus, the preparation method thereof and the use thereof in manufacturing medicaments against tumors, especially liver cancer.
Public/Granted literature
- US20110112061A1 PYRIDAZINONES, THE PREPARATION AND THE USE THEREOF Public/Granted day:2011-05-12
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