Invention Grant
US08501741B2 Optically active compound of prulifloxacin for treating infection and preparation method thereof
有权
用于治疗感染的普利氟沙星的光学活性化合物及其制备方法
- Patent Title: Optically active compound of prulifloxacin for treating infection and preparation method thereof
- Patent Title (中): 用于治疗感染的普利氟沙星的光学活性化合物及其制备方法
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Application No.: US13522290Application Date: 2010-10-22
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Publication No.: US08501741B2Publication Date: 2013-08-06
- Inventor: Jun Ying , Feng Peng , Yuping Wang , Suiwei An , Jinqiang Liang , Beimei Liang , Qingchun Ni , Cheng Luo
- Applicant: Jun Ying , Feng Peng , Yuping Wang , Suiwei An , Jinqiang Liang , Beimei Liang , Qingchun Ni , Cheng Luo
- Applicant Address: CN Hainan
- Assignee: Hainan Hualon Pharmaceutical Co., Ltd.
- Current Assignee: Hainan Hualon Pharmaceutical Co., Ltd.
- Current Assignee Address: CN Hainan
- Agency: Christie, Parker, Hale, LLP
- Priority: CN201010019328 20100113
- International Application: PCT/CN2010/078020 WO 20101022
- International Announcement: WO2011/085606 WO 20110721
- Main IPC: A61K31/496
- IPC: A61K31/496 ; C07D495/04
Abstract:
Anti-infection levorotatory optically active compound (S-configuration) of prulifloxacin represented by the following formula (1) and preparation method thereof are disclosed. Said method utilizes levorotatory ulifloxacin as the raw material and the reaction is conducted in organic solvent in the presence of alkaline materials, wherein the reaction temperature is −20° C.˜60° C. and the reaction time is 15 minutes to 24 hours.
Public/Granted literature
- US20120302580A1 OPTICALLY ACTIVE COMPOUND OF PRULIFLOXACIN FOR TREATING INFECTION AND PREPARATION METHOD THEREOF Public/Granted day:2012-11-29
Information query
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