Invention Grant
- Patent Title: Tetrahydroprotoberberine compounds, the synthetic method and the use thereof
- Patent Title (中): 四氢丙泊嗪化合物，合成方法及其用途
-
Application No.: US11988441Application Date: 2006-07-07
-
Publication No.: US08501762B2Publication Date: 2013-08-06
- Inventor: Jianfeng Li , Aixiang Liu , Xinjian Chen , Guozhang Jin , Tiema Yan , Rongxia Zhang , Yi Zhu , Yanjun Pan , Jingshan Shen , Jingkang Shen
- Applicant: Jianfeng Li , Aixiang Liu , Xinjian Chen , Guozhang Jin , Tiema Yan , Rongxia Zhang , Yi Zhu , Yanjun Pan , Jingshan Shen , Jingkang Shen
- Applicant Address: CN Shanghai CN Shanghai
- Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Topharman Shanghai Co., Ltd.
- Current Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences,Topharman Shanghai Co., Ltd.
- Current Assignee Address: CN Shanghai CN Shanghai
- Agency: Nixon & Vanderhye PC
- Priority: CN200510027630 20050708
- International Application: PCT/CN2006/001601 WO 20060707
- International Announcement: WO2007/006212 WO 20070118
- Main IPC: A61K31/4353
- IPC: A61K31/4353 ; C07D221/18
Abstract:
The present invention relates to tetrahydroprotoberberines of the formula (I) and the physiologically acceptable salts thereof. The invention also relates to the use of the compounds of the formula (I) or pharmaceutically acceptable salts thereof for preparing a pharmaceutical composition for the treatment of a medical disorder susceptible to treatment with dopamine receptor ligand, such as schizophrenia.
Public/Granted literature
- US20090149488A1 Tetrahydroprotoberberine Compounds, the Synthetic Method and the Use Thereof Public/Granted day:2009-06-11
Information query
