Invention Grant
- Patent Title: 4-fluoro-piperidine T-type calcium channel antagonists
- Patent Title (中): 4-氟哌啶T型钙通道拮抗剂
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Application No.: US11922399Application Date: 2006-06-28
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Publication No.: US08501773B2Publication Date: 2013-08-06
- Inventor: James C. Barrow , Craig W. Lindsley , William D. Shipe , Zhiqiang Yang , David Wisnoski
- Applicant: James C. Barrow , Craig W. Lindsley , William D. Shipe , Zhiqiang Yang , David Wisnoski
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent J. Eric Thies; Gerard M. Devlin
- International Application: PCT/US2006/025496 WO 20060628
- International Announcement: WO2007/002884 WO 20070104
- Main IPC: A01N43/42
- IPC: A01N43/42 ; A01N43/40 ; A61K31/47 ; A61K31/445 ; C07D211/00 ; C07D295/00 ; C07D211/08 ; C07D401/00 ; C07D405/00 ; C07D409/00 ; C07D411/00 ; C07D413/00 ; C07D417/00 ; C07D419/00 ; C07D421/00
Abstract:
The present invention is directed to 4-fluoro-piperidine compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved.
Public/Granted literature
- US20100216841A1 4-Fluoro-Piperidine T-Type Calcium Channel Antagonists Public/Granted day:2010-08-26
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