Invention Grant
US08501786B2 Hydroxymethyl pyrrolidines as beta 3 adrenergic receptor agonists
有权
羟甲基吡咯烷作为β3肾上腺素能受体激动剂
- Patent Title: Hydroxymethyl pyrrolidines as beta 3 adrenergic receptor agonists
- Patent Title (中): 羟甲基吡咯烷作为β3肾上腺素能受体激动剂
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Application No.: US12936275Application Date: 2009-03-23
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Publication No.: US08501786B2Publication Date: 2013-08-06
- Inventor: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Bart Harper , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Harvey Wendt , Cheng Zhu
- Applicant: Richard Berger , Lehua Chang , Scott D. Edmondson , Stephen D. Goble , Bart Harper , Nam Fung Kar , Ihor E. Kopka , Bing Li , Gregori J. Morriello , Chris R. Moyes , Dong-Ming Shen , Liping Wang , Harvey Wendt , Cheng Zhu
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Patricia A. Shatynski; Valerie J. Camara
- International Application: PCT/US2009/037911 WO 20090323
- International Announcement: WO2009/123870 WO 20091008
- Main IPC: A61K31/443
- IPC: A61K31/443 ; A61K31/4436 ; A61K31/4439 ; C07D401/14 ; C07D413/14 ; C07D417/14
Abstract:
The present invention provides compounds of Formula I, pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
Public/Granted literature
- US20110028461A1 HYDROXYMETHYL PYRROLIDINES AS BETA 3 ADRENERGIC RECEPTOR AGONISTS Public/Granted day:2011-02-03
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