Invention Grant
- Patent Title: Compounds for the treatment of proliferative disorders
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Application No.: US13252423Application Date: 2011-10-04
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Publication No.: US08501790B2Publication Date: 2013-08-06
- Inventor: Zachary Demko , Christopher Borella , Shoujun Chen , Lijun Sun
- Applicant: Zachary Demko , Christopher Borella , Shoujun Chen , Lijun Sun
- Applicant Address: US MA Lexington
- Assignee: Synta Pharmaceuticals Corp.
- Current Assignee: Synta Pharmaceuticals Corp.
- Current Assignee Address: US MA Lexington
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Wei Song
- Main IPC: A61K31/41
- IPC: A61K31/41 ; C07D249/00
Abstract:
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
Public/Granted literature
- US20120022118A1 COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS Public/Granted day:2012-01-26
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