Invention Grant
US08501796B2 Ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for lowering intraocular pressure
有权
用于降低眼内压的[3-(1-(1H-咪唑-4-基)乙基)-2-甲基苯基]甲酯的酯前体药物
- Patent Title: Ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for lowering intraocular pressure
- Patent Title (中): 用于降低眼内压的[3-(1-(1H-咪唑-4-基)乙基)-2-甲基苯基]甲酯的酯前体药物
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Application No.: US13233844Application Date: 2011-09-15
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Publication No.: US08501796B2Publication Date: 2013-08-06
- Inventor: Mohammad I. Dibas , Daniel W. Gil , John E. Donello , Ken Chow , Liming Wang , Michael E. Garst
- Applicant: Mohammad I. Dibas , Daniel W. Gil , John E. Donello , Ken Chow , Liming Wang , Michael E. Garst
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agent Doina G. Ene
- Main IPC: A61K31/415
- IPC: A61K31/415
![Ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for lowering intraocular pressure](/abs-image/US/2013/08/06/US08501796B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to method of lowering intraocular pressure in a subject in need of such treatment, which comprises administering a therapeutically effective amount of a composition comprising a ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl]methanol, of enantiomers thereof, of tautomers thereof, pharmaceutical compositions containing them and their use as pharmaceuticals.
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